Preventive Nutrition and Food Science

The Korean Society of Food Science and Nutrition (한국식품영양과학회)
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Antimutagenic Compounds Indentified from Chloroform Fraction of Persimmon Leaves

  • Moon, Suk-Hee (Dept. of Food and Nutrition, Kyungnam junior College) ;
  • Jeong-Ok kim (Dept .of Chemistry, Pusan Women's University) ;
  • Park, Kun-Young (Dept. of food Science and Nutrition, Pusan National University)
  • Published : 1996.10.01
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Abstract

Methanol extract of dried persimmon leaves was refractionated using hexane, chloroform, ethylacetate, n-butanol aqueous fractions. Among these chloroform fraction showed the highest inhibition rate on the mutagenicities of aflatoxin B₁(AFB₁) and 3,2' -dimethyl-4-amino-bipheny1(DMAB) in Salmonella typhimurium TA 100. Chloroform fraction was further fractionated into eight fractions by silica gel column chromatography and thin layer chromatography(TLC). The fraction 5 on TLC exhibited the highest antimutagenic activities in AFB₁and DMAB. 2,4-Decadienal, dihydro-4-methyl-2(3H)-furanone, hexanoic acid 1,4-bis(1-methy1 ethy1)benzene, heptanoic acid, phenol, octanoic acid, nonanoic acid and benzoic acid were tentatively identified from this antimutagenic fraction by GC-MS.

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References

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