Toxicological Research

Korean Society of Toxicology & Korea Environmental Mutagen Society (한국독성학회)
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Acute Oral Toxicity of KDRD-010 in Rats

랫드에 대한 KDRD-010의 급성경구독성시험

  • 곽승준 (성균관대학교 약학대학 독성학교실) ;
  • 김형식 (성균관대학교 약학대학 독성학교실) ;
  • 천선아 (성균관대학교 약학대학 독성학교실) ;
  • 임소영 (성균관대학교 약학대학 독성학교실) ;
  • 홍채영 (성균관대학교 약학대학 독성학교실) ;
  • 박현선 (성균관대학교 약학대학 독성학교실) ;
  • 최병천 (광동제약 중앙연구소) ;
  • 이병무 (성균관대학교 약학대학 독성학교실)
  • Published : 1996.12.01
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Abstract

This study was carried out to investigate the acute toxicity of KDRD-010 in Sprague-Dawley rats. KDRD-010 was administratered orally at a dose level of 26, 78, 233, 700, and 2,100 mg/kg. In this study, we daily examined number of deaths, clinical signs, body weights, and pathological examinations for 14 days after administration of KDRD-010. The results indicate that KDRD-010 did not show any toxic effect in rats and oral $LD_50$ value was over 2,100 mg/kg in Sprague-Dawley rats.

Keywords

References

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