Journal of Biomedical Engineering Research (대한의용생체공학회:의공학회지)

The Korean Society of Medical and Biological Engineering (대한의용생체공학회)
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Spontaneous Firing Characteristics of Cardiovascular Neurons in the Rostral Ventrolateral Medulla During Somatosympathetic Reflex : II. Minimal Neuronal Model

상부복외측 연수 심혈관계 세포의 체성교감반사시 자발적 흥분발사특성 분석 : I. 실험적 연구

  • 차은종 (충북대학교 의과대학 생리학교실, 의공학교실) ;
  • 구용숙 (충북대학교 의과대학 생리학교실, 의공학교실) ;
  • 이태수 (충북대학교 의과대학 생리학교실, 의공학교실)
  • Published : 1996.03.01
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Abstract

A number of experimental evidences suggest that the rnun ventrolateral medulla(RVLM) is the final common pathway in the regulation of arterial blood pressure. A Voup of neurons in the RVLM, called the cardiovascular neurons (UN), show spontaneous activity temporally synchronized with the periodic cardiac cycle. These neurons affect the sympathetic nerve discharge(SND), thus are believed to be responsible for blood pressure control. The present experiment identified 98 UVNs in 42 cats based on the temporal relationships between each neuron's activity with both the cardiac cycle and SWD. In 20 UWL changes of spontaneous firing rate(FR) during the somatosympathetic reflex(SSR) were studied Five different firing patterns were observed during the pressor and depressor responses of SSR, implying that they form an interconnected neuronal circuit interacting with one another to generate efferent signals for blood pressure regulation. In the following companion paper, the firing patterns of CVN are analyzed to develop a minimal neuronal circuit model explaining the present experimental outcome.

Keywords

References

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