Journal of Biomedical Engineering Research (대한의용생체공학회:의공학회지)

The Korean Society of Medical and Biological Engineering (대한의용생체공학회)
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Metal Ion Release Behaviour and Cytotoxicity of a Super Stainless Steel

초내식성 스테인레스강의 금속이온용출특성 및 세포적합성

  • Kim, Cheol-Sang (Department of Biomedical Engineering, College of Medicine, Kon Kuk University) ;
  • Park, Jin-Soo (Department of Immunology, College of Medicine, Kon Kuk University) ;
  • Her, Erk (Department of Immunology, College of Medicine, Kon Kuk University) ;
  • Khang, Gon (Department of Biomedical Engineering, College of Medicine, Kon Kuk University)
  • 김철생 (건국대학교 의과대학 의학공학과) ;
  • 박진수 (건국대학교 의과대학 면역학교실) ;
  • 허억 (건국대학교 의과대학 면역학교실) ;
  • 강곤 (건국대학교 의과대학 의학공학과)
  • Published : 1996.03.01
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Abstract

The toxic metal ion release behaviour and the cytotoxicity of a super stainless steel (S.S.S, 22cr-20Ni -6Mo-0.25N) were investigated The measurement of the amount of static and wear- induced trace metal ion released from the steels was conducted in Hank's balanced salt solution using an electrothermal atomic absdrption spectrometry equiped with Uaphite furnace. And the in vitro cytotoxicity of the materials was assesed in cell culture. The static dissolution rates of Fe and Cr ions from the S.S.S were significantly lower than those of 316L SS. However, the Ni ion release from the S.S.S during the first 4 weeks was yester than that from 316L 55 by 15-45%. Also, the wear-in- duces dissolution rates from the steels were not correlated either with their elemental composition rates or with the static metal ion release rates. The S.S.S did not deteriorate the osteoblasts viability. And no toxic response was observed from the macrophages cultured for 7 days in RFMI 1640 medium immersed with the S.S.S specimens.

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