The Journal of Internal Korean Medicine (대한한방내과학회지)

The Society of Internal Korean Medicine (대한한방내과학회)
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Studies on the Effect of Sangphisan on thePulmonary Edema of the rat induced by the Herbicide, Paraquat

상피산(桑皮散)이 Paraquat로 유발(誘發)시킨 랫트의 폐수종(肺水腫)에 미치는 영향(影響)

  • Choi, Byung-Kab (Dept. of Oriental Medicine Graduate school of Won Kwang University) ;
  • Shin, Jo-Young (Dept. of Oriental Medicine Graduate school of Won Kwang University)
  • 최병갑 (원광대학교 한의과대학 폐계내과학교실) ;
  • 신조영 (원광대학교 한의과대학 폐계내과학교실)
  • Published : 1996.03.30
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Abstract

Sangphisan, sangphisan with Cortex Mori Cortex Lycii, Semen Lepidh were administrated into rats and then they were injected by Paraquat. The results are as follows 1. After 72 hours following the injection of paraquat, the survival rate of rats increased Sangphisan, Sangphisan with Cortex Mori Cortex Lycii Group. 2. Respirayory rates of rats witch survived 72 hours later significantly decreased in sangphisan, sangphisan with Semen Lepidh. 3. Lung weights of rats which survived for 72 hours later significantly decreased in Sangphisan, Sangphisan with Cortex Mori Cortex Lycii and mild decreased in Sangphisan with Semen Lepidh. 4. After the injection of paraquat, a lung tissue showed severe hemorrhage, edema and some broken aibeoli and Sangphisan, sangphisan with Cortex Mori Cortex Lycii, Sangphisan with Semen Lepidh recovered significantly.

Keywords

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