The Journal of Korean Medicine (대한한의학회지)

The Society of Korean Medicine (대한한의학회)
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Effects of Rehmannia Radix Water Extracts on the Plasma Renin Activity and Plasma Levels of Aldosterone and Atrial Natriuretic Peptide in Rats

지황(地黃) 전탕액(煎湯液) 투여(投與)가 백서(白鼠)의 혈장(血漿) Renin 활성도(活性度), 혈장(血漿) Aldosterone 및 Atrial Natriuretic Peptide 농도(濃度)에 미치는 영향(影響)

  • 이호섭 (원광대학교 한의과대학 생리학교실) ;
  • 류도곤 (원광대학교 한의과대학 생리학교실) ;
  • 윤용갑 (전주 갑자원 한의원) ;
  • 유윤조 (우석대학교 한의과대학 생리학교실)
  • Published : 1996.04.30
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Abstract

Rehmannia Radix is a thick tuberous root about 3-6 cm diameter. The tuberous root is repared for medicine. The material in the fresh state is shengdihuang (生地黃). The material in the dried state is gandihuang (乾地黃). Shudihuang (熱地黃) is made by taking juicy roots, washing them in millet wine, steaming on a willow frame in a percelain vessel, drying, and resteaming and redrying nine times. The aim of this experiments was to investigate the effect of Rehmannia Radix Water extracts on the plasma renin activity and plasma levels of aldosterone and atrial natriuretic peptide (ANP) in rats. The results of study were as follows: Plasma renin activity was not changed after administration of Rehmannia Radix water extracts. Plasma levels of aldosterone was decreased significantly after administration of Shudihuang (熱地黃) water extracts. Plasma levels of atrial natriuretic peptide was increased significantly after administration of Shudihuang (熱地黃) water extracts.

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