Journal of the korean academy of Pediatric Dentistry (대한소아치과학회지)

Korean Academy of Pediatric Dentistry (대한소아치과학회)
권호 표지

IMMUNOHISTOCHEMICAL STUDY ON THE POSTNATAL DEVELOPMENT OF DENTAL PULP INNERVATION IN RAT POSTERIOR TEETH

출생후 흰쥐 구치의 발육에 따른 치수의 신경지배 발달에 관한 면역조직화학적 연구

  • Kim, Dong-Gil (Dept. of Pediatric, School of Dentistry Kyungpook National University) ;
  • Kim, Hyun-Jung (Dept. of Pediatric, School of Dentistry Kyungpook National University) ;
  • Nam, Soon-Hyun (Dept. of Pediatric, School of Dentistry Kyungpook National University) ;
  • Bae, Yong-Chul (Dentistry and Oral Anatomy, School of Dentistry Kyungpook National University) ;
  • Kim, Young-Jin (Dept. of Pediatric, School of Dentistry Kyungpook National University)
  • 김동길 (경북대학교 치과대학 소아치과학교실) ;
  • 김현정 (경북대학교 치과대학 소아치과학교실) ;
  • 남순현 (경북대학교 치과대학 소아치과학교실) ;
  • 배용철 (경북대학교 치과대학 구강해부학교실) ;
  • 김영진 (경북대학교 치과대학 소아치과학교실)
  • Published : 1996.11.30
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Abstract

The purpose of this study was to investigate the postnatal development of pulpal innervation with the tooth development and eruption process in developing rat mandibular molars (postnatal 1, 5, 10, 15, 20, 25, 35day-old and adult rats). Immunohistochemical method was carried out for the detection of nerve fibers, using the antibody against calcitonin gene-related peptide(CGRP). The results were as follows: The feature of CGRP-IR nerve fibers were shown in a bead-like appearance. The time of nerve entering into the dental papilla of tooth follicle began at the occured advanced dentinogenesis. The development of Raschkow plexus began at the formative stage of the roots and was accelerated at the stage of the crown emerged into the oral cavity. The number of nerve fibers entering the odontoblastic layer increased with the tooth eruption and mastication. The development of innervation was shown to be related with the stage of the development of individual teeth rather than the chronological age of the rat.

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