한국한의학연구원논문집 (Korean Journal of Oriental Medicine)
- 제2권1호
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- Pages.129-145
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- 1996
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- 1229-3377(pISSN)
약침용 홍삼추출액의 면역독성, 발열성 및 용혈성시험에 관한 연구
Studies on the Safety Assessment of Red-ginseng Radix Extract Solution for Herb-acupuncture (III)
- Nam, Yun-Seok (Dept. of acupuncture and moxibustion, College of Oriental Medicine, Kyunghee Univ.) ;
- Lee, Yun-Ho (Dept. of acupuncture and moxibustion, College of Oriental Medicine, Kyunghee Univ.)
- 발행 : 1996.12.30
초록
According to the Medical Product Safety Administration Guidelines for safety assessment guinea pigs, mice and rats were used for antigenicity test, rabbits for pyrogenic test and hymolytic test. The results were summarized as follows; 1. The antigenicity test of Red-ginseng radix extract solution for herb-acupuncture did not show any anaphylatic shock but produced IgE in high dose group. 2. The result of the pyrogen test of Red-ginseng radix extract solution for herb-acupuncture was negative. 3. The result of the hemolytic test of Red-ginseng radix extract solution for herb-acupuncture were negative in low and middle dose group but was positive in high dose group.