생약학회지 (Korean Journal of Pharmacognosy)

  • 제27권2호
  • /
  • Pages.105-110
  • /
  • 1996
  • /
  • 0253-3073(pISSN)
  • /
  • 2288-9299(eISSN)
한국생약학회 (The Korean Society of Pharmacognosy)
권호 표지

전통 약용식물 및 각종 식물의 항암 효과에 대한 연구 (III)

Antineoplastic Effect of Extracts from Traditional Medicinal Plants and Various Plants (III)

  • 현진원 (서울대학교 의과대학 암연구소 및 암연구센터 세포생물학 연구부) ;
  • 임경화 (서울대학교 의과대학 암연구소 및 암연구센터 세포생물학 연구부) ;
  • 성민숙 (서울대학교 의과대학 암연구소 및 암연구센터 세포생물학 연구부) ;
  • 강삼식 (서울대학교 천연물과학연구소) ;
  • 백우현 (보령제약 주식회사 중앙연구소) ;
  • 배건우 (보령제약 주식회사 중앙연구소) ;
  • 조현 (보령제약 주식회사 중앙연구소) ;
  • 김형자 (한국과학기술연구원) ;
  • 우은란 (한국과학기술연구원) ;
  • 박호군 (한국과학기술연구원) ;
  • 박재갑 (서울대학교 의과대학 암연구소 및 암연구센터 세포생물학 연구부) ;
  • 양용만 (서울대학교 의과대학 암연구소 및 암연구센터 세포생물학 연구부)
  • Hyun, Jin-Won (Laboratory of Cell Biology, Cancer Research Institute and Cancer Research Center, Seoul National University, College of Medicine) ;
  • Lim, Kyoung-Hwa (Laboratory of Cell Biology, Cancer Research Institute and Cancer Research Center, Seoul National University, College of Medicine) ;
  • Sung, Min-Sook (Laboratory of Cell Biology, Cancer Research Institute and Cancer Research Center, Seoul National University, College of Medicine) ;
  • Kang, Sam-Sik (Natural Products Research Institute, Seoul National university) ;
  • Paik, Woo-Hyun (Central Research Institute, Boryung Pharmaceutical Co., Ltd.) ;
  • Bae, Kun-Woo (Central Research Institute, Boryung Pharmaceutical Co., Ltd.) ;
  • Cho, Hyun (Central Research Institute, Boryung Pharmaceutical Co., Ltd.) ;
  • Kim, Hyoung-Ja (Division of Applied Science, Korea Institute of Science and Technology) ;
  • Woo, Eun-Rhan (Division of Applied Science, Korea Institute of Science and Technology) ;
  • Park, Ho-Koon (Division of Applied Science, Korea Institute of Science and Technology) ;
  • Park, Jae-Gahb (Laboratory of Cell Biology, Cancer Research Institute and Cancer Research Center, Seoul National University, College of Medicine) ;
  • Yang, Yong-Man (Laboratory of Cell Biology, Cancer Research Institute and Cancer Research Center, Seoul National University, College of Medicine)
  • 발행 : 1996.06.30
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초록

Antineoplastic activity against human gastric and colon carcinoma cell lines was tested in eighty-three species of Korean plants including Korean medicinal plants which have been frequently used in oriental herb prescriptions. The plant materials were extracted with methanol and the cytotoxic activity was tested using a calorimetric tetrazolium assay (MTT assay). Twenty-six plant extracts against gastric carcinoma cell line, eighteen extracts against colon carcinoma cell line and fourteen plant extracts against both carcinoma cell lines showed antineoplastic activity at the concentration of less than $100{\mu}g/ml$. The effective components from four species have been isolated and reported.

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