생약학회지 (Korean Journal of Pharmacognosy)
- 제27권1호
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- Pages.37-41
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- 1996
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- 0253-3073(pISSN)
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- 2288-9299(eISSN)
생약복합제제 길경탕 및 가미길경탕의 항암효과 (제 1 보)
Antitumor Activity of the Medicinal Formula Kilkyungtang and Two Modified Kilkyungtangs in Vivo. I
- Kim, Sung-Hoon (Oriental Medical College, Taejeon University) ;
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Park, Kyung-Sik
(Oriental Medical College, Sangji University) ;
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Ryu, Shi-Yong
(Korea Research Institute of Chemical Technology)
- 발행 : 1996.03.30
초록
The prescription, Kilkyungtang (KKT), which originally consists of twelve kinds of medicinal plant materials and was used as a decoction for the treatment of malignant tumors and two modified Kilkyungtangs (KKT-1 and KKT-2), supplemented by the additional crude drug to KKT (KKT-1:Houttuyniae herba, and KKT-2:Oldenlandiae diffusae herba) were investigated on their antitumoral properties, in vivo respectively. All KKTs were found to exhibit significant life time-prolonging effects when they were administered orally to Sarcoma-180 bearing ICR mice for 7 days. (ILS was estimated as 20% in KKT, 42% in KKT-1 and 57% in KKT-2). A profound lessening of tumor weights was also observed when KKTs were administered to