새로운 AIDS 치료제로서 3'-메틸아미노 피리미딘의 합성

Sythesis of 3'-Methylamino Pyrimidine as Potential Anti AIDS Agents

  • 백기현 (배재대학교 이공대학 화학과) ;
  • 윤인권 (배재대학교 이공대학 화학과)
  • 발행 : 1995.02.18

초록

3'-Methylamino pyrimidine 3 was prepared from deoxy pyrimidine via the following 8 step reaction sequences; silyl protection, mesylation, cyclization, azide substitution, hydrogenation, t-Boc protection, methylation, and deprotection in 23% overall yield as a potential anti-AIDS agents.

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