Effect of Naganjeon on the hepatoxicity of carbo tetrachloride in rats

난간전(煖肝煎)이 carbon tetrachloride로 유도(誘導)한 간중독(肝中毒) 흰쥐에 미치는 영향(影響)

  • Jung, sung Yee (Dept. of Oriental Prescription, College of Oriental Medicine, Dong Guk Univ.) ;
  • Park, Sun Dong (Dept. of Oriental Prescription, College of Oriental Medicine, Dong Guk Univ.)
  • 정성이 (동국대학교 한의과대학 방제학교실) ;
  • 박선동 (동국대학교 한의과대학 방제학교실)
  • Published : 1995.12.20

Abstract

The purpose of this study is to observe the effect of Nanganjeon on serum reaction in $CCl_4$ treated rats. In this study, the experimental rats divided four group(Control group, $CCl_4$ group, Haeganjeon group, and Sample group) : Under the same condition, control group were administered water, sample group were administered Nanganjeon for 7days. And then, both $CCl_4$ group and sample group were injected to abdomen with $CCl_4$ for 1days. The change of GOT, GPT, ALP, LDH, and bile acid activity in blood serum. The obtained results are summarised as follows : 1. In the change of SGOT, SGPT contents, as compared with control group, sample group was significantly decreased. 2. In the change of serum ALP contents, as compared with control group, sample group was significantly decreased. 3. In the change of serum bile acid contents, as compared with control group, sample group was significantly decreased. 4. In the change of serum LDH contents, as compared with control group, sample group was significantly decreased.

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