Multiple Brain Calcification in Chronic Lead Poisoning

만성 연중독자에서의 다발성 뇌석회화 병변

  • 김성률 (동아의료원 건강관리과) ;
  • 김병권 (동아의료원 건강관리과) ;
  • 홍영습 (동아의료원 건강관리과) ;
  • 담도온 (동아의료원 건강관리과) ;
  • 최순섭 (동아대학교 의과대학 예방의학교실 및 산업의학연구소, 동아의료원 진단방사선과) ;
  • 정갑열 (동아의료원 건강관리과) ;
  • 김준연 (동아의료원 건강관리과)
  • Published : 1995.06.01

Abstract

We experienced a case of occupational lead poisoning employed in a secondary lead smelting plant for 12 years. The patient was 39-year-old male and had been felt dizziness, recent memory impairment and intermittent severe abdominal pain for 2 years. On admission, blood lead level was $92.9{\mu}g/dl$, urinary lead level was $19.9{\mu}g/l$ and zinc protoporphyrin level was $226.0{\mu}g/dl$. On the blood test, hemoglobin was 10.6g/dl and showed normocytic normochromic anemia. There were no abnormal findings in the biochemical and hormonal tests. Decrease of I.Q. and use of words in speaking were found in the psychiatric and psychologic examinations. We observed the finding of motor polyneuropathy in the nerve conduction velocity test. Computed tomographic finding showed calcification lesions in the basal ganglia, dentate nuclei, caudate nuclei, and especially characteristic multiple calcifications were located in the subcortical white matter.

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