Maxillofacial Plastic and Reconstructive Surgery
- 제17권4호
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- Pages.350-364
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- 1995
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- 2288-8101(pISSN)
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- 2288-8586(eISSN)
동종 탈회골의 크기가 유도골 형성에 미치는 영향에 관한 실험적 연구
EXPERIMENTAL STUDY OF EFFECT ON INDUCED OSTEOGENESIS ACCORDING TO THE SIZE OF DEMINERALIZED ALLOGENEIC BONE
- 방만혁 (원광대학교 치과대학 구강악안면외과학교실) ;
- 엄인웅 (원광대학교 치과대학 구강악안면외과학교실) ;
- 이동근 (원광대학교 치과대학 구강악안면외과학교실) ;
- 민승기 (원광대학교 치과대학 구강악안면외과학교실)
- Bang, Man-Hyeok (Dept. of Oral and Maxillofacial Surgery, College of Dentistry, Wonkwang University) ;
- Um, In-Woong (Dept. of Oral and Maxillofacial Surgery, College of Dentistry, Wonkwang University) ;
- Lee, Dong-Keun (Dept. of Oral and Maxillofacial Surgery, College of Dentistry, Wonkwang University) ;
- Min, Seung-Ki (Dept. of Oral and Maxillofacial Surgery, College of Dentistry, Wonkwang University)
- 발행 : 1995.12.31
초록
As early as 1889, treatment of ostemyelitis was reported using xenogeneic demineralized bone. In 1965, Urist discovered that demineralized long bone fragment, even when implanted in nonskeletal tissue, would stimulate osteogenesis. The clinical use of demineralized bone of Oral and Maxillofacial surgery is not new. The demineralized bone implants were used for 1) interposition within osteotomy gaps, cystic detects, alveolar clefts ; 2) augmentation, over intact bone surfaces ; 3) construction of new bone within soft tissue. Demineralized bone grafts invokes a induced osteogenesis which is the transformation of host cells into osteoblasts. Demineralized bone has identified several factors that modulate the osteogeneic response : sterilization method, recipient age, particle size etc. Especially, pulverization of bone matrix may enhance its osteoinductive properties, to allow rapid, efficient bridging of large defects. the purpose of the present report was to describe the potential efficacy of demineralized allogeneic bone powder of skull of rabbits as a particle size ; 212
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