Maxillofacial Plastic and Reconstructive Surgery

Korean Association of Maxillofacial Plastic and Reconstructive Surgeons (대한악안면성형재건외과학회)
권호 표지

AN EXPERIMENTAL STUDY ON THE OSTEOGENESIS BY FREEZE-DRIED DEMINERALIZED ALLOGENEIC BONE AND BIOGLASS

냉동 건조 탈회 동종골과 Bioglass의 골형성에 관한 실험적 연구

  • Min, Seung-Ki (Dept. of Oral and Maxillofacial Surgery, School of Dentistry, Wonkwang University) ;
  • Lee, Dong-Keun (Dept. of Oral and Maxillofacial Surgery, School of Dentistry, Wonkwang University) ;
  • Um, In-Woong (Dept. of Oral and Maxillofacial Surgery, School of Dentistry, Wonkwang University) ;
  • Moon, Cheol (Dept. of Oral and Maxillofacial Surgery, School of Dentistry, Wonkwang University) ;
  • Lee, Eun-Yeong (Dept. of Oral and Maxillofacial Surgery, School of Dentistry, Wonkwang University)
  • 민승기 (원광대학교 치과대학 구강악안면 외과학교실) ;
  • 이동근 (원광대학교 치과대학 구강악안면 외과학교실) ;
  • 엄인웅 (원광대학교 치과대학 구강악안면 외과학교실) ;
  • 문철 (원광대학교 치과대학 구강악안면 외과학교실) ;
  • 이은영 (원광대학교 치과대학 구강악안면 외과학교실)
  • Published : 1995.06.30
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Abstract

This study was designed to evaluate the bone formation capability of the bone substitute when compared with autogenic bone, freeze-dried demineralized allogeneic bone and bioglass into parietal bone of the rats. We made the parietal bone defects in $7{\times}7mm$ size on rats and has performed the bone graft in each experimental groups. Postoperatively 1, 2, 4, 6, 8, weeks, each specimen stained with H & E, Masson's trichrome methods. We evaluated the osteogensis capability in each groups. The result were as follow : 1. Inflammatory cell infiltration approached at 1 week and disappeared at 4 weeks in all experimental group, expecially severe in freeze-dried demineralized allogeneic bone group. 2. New capillry proliferation was increased in autogeneic bone graft group than any other groups and was increased till 2 weeks and decreased in freeze-dried demineralized allogeneic bone group and was few in bioglass group. 3. Osteoblastic activity increased in autogeneic bone and freeze-dried demineralized allogeneic bone groups till 4 weeks, and decreased in 6 weeks which no difference between these groups. But, few occurred in bioglass group till 6 weeks. 4. Initial osteoclastic activity was prominent in freeze-dried demineralized allogeneic bone group and few in autogeneic bone group. 5. New bone formation bega at 1 week in autograft and freeze-dried demineralized allogenic bone groups, but, mild new bone formation at 8 weeks in bioglass.

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