Pediatric Infection and Vaccine

The Korean Society of Pediatric Infectious Diseases (대한소아감염학회)
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A study of serum lipid level and relation between the serum lipid level and coronary aneurysm after kawasaki disease

가와사끼병에서 혈청 지질 대사의 변화 및 관상동맥류에 관한 연구

  • Chung, Churl Young (Department of pediatrics, College of Medicine, Inje university, Paik Hospital) ;
  • Kim, Chang Keun (Department of pediatrics, College of Medicine, Inje university, Paik Hospital)
  • 정철영 (인제대학교 의과대학 상계백병원 소아과학교실) ;
  • 김창근 (인제대학교 의과대학 상계백병원 소아과학교실)
  • Published : 1995.11.25
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Abstract

We measured plasma concentrations of high density lipoprotein, total cholesterol and triglycerides in 31 patients with history of kawasaki disease during acute stage and convalescence stage. High density lipoprotein cholesterol and total cholesterol concentrations were significantly lower(P<0.001) in samples taken within 11 days of the onset of illness($28.7{\pm}12.4mg/dl$ and $145.20{\pm}29.60mg/dl$) than in the second samples taken 1-2months after onset of disease($51.5{\pm}15.2mg/dl$ and $175.4{\pm}29.0mg/dl$). Change of triglycerides was not significant. There was no correlation between the serum cholesterol cencentration and coronary aneurysm and continued long term surveillance of much population is necessary to monitor lipid level and their relation to development of premature coronary atherosclerosis.

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