Journal of the Korean Chemical Society (대한화학회지)

Korean Chemical Society (대한화학회)
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Synthesis of New 2-Amino-4-methylcyano-5-methylsulfonylpyrimidine Derivatives

새로운 2-Amino-4-methylcyano-5-methylsulfonylpyrimidine 유도체들의 합성

  • Kim, Jung-Hwan (Department of Chemistry, Yeungnam University) ;
  • Han, Mun-Su (Department of Chemistry, Yeungnam University) ;
  • Kim, Un-Ju (Department of Chemistry, Yeungnam University)
  • 김정환 (영남대학교 이과대학 화학과) ;
  • 한문수 (영남대학교 이과대학 화학과) ;
  • 김은주 (영남대학교 이과대학 화학과)
  • Published : 19950900
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Abstract

The derivatives of 2-amino-4-methylcyano-5-methylsulfonylpyrimidine 6 containing chloro, methoxy, ethoxy, phenoxy, amino and anilino groups at 6-position on the pyrimidine ring were prepared from 2-amino-4-chloro-5-methylsulfonylpyrimidine derivatives 4 and tert-butylcyanoacetate. The derivatives of 2-amino-4-chloro-5-methylsulfonylpyrimidine 4 containing methoxy, ethoxy, isopropoxy, phenoxy, amino and anilino groups at 6-position on the pyrimidine ring were prepared from 2-amino-4,6-dichloro-5-methylsulfonylpyrimidine 3.

Pyrimidine의 6번위치에 chloro, methoxy, ethoxy, amino, 및 amino 기가 도입된 2-amino-4-methylcyano-5-methylsulfonylpyrimidine 유도체 6들은 2-Amino-4-methylcyano-5-methylsulfonylpyrimidine 유도체 4들과 tert-butylcyanoacetate로부터 합성되었으며 pyrimidine의 6번 위치에 methoxy, ethoxy, isopropoxy, phenoxy, amino 및 anilino기가 도입된 2-amino-4-methylcyano-5-methylsulfonylpyrimidine 유도체 4들은 2-amino-4-methylcyano-5-methylsulfonylpyrimidine 3으로부터 합성되었다.

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References

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