한국환경과학회지 (Journal of Environmental Science International)

  • 제4권5호
  • /
  • Pages.543-549
  • /
  • 1995
  • /
  • 1225-4517(pISSN)
  • /
  • 2287-3503(eISSN)
한국환경과학회 (The Korean Environmental Sciences Society)
권호 표지

Drosophila meianogaster에서 Ethyl methanesulfonate에 의한 반성 치사 돌연변이 유발성의 비교

Comparative Induction of Sex-linked lethal mutations in Drosophila melanogaster males by Ethyl methanesulfonate

  • 최영현 (부산대학교 자연과학대학 생물학과) ;
  • 유미애 (부산대학교 자연과학대학 분자생물학과) ;
  • 이원호 (부산대학교 자연과학대학 생물학과)
  • Choi, Yung-Hyun (Dept. of Biology, College of Natural Science, Pusan National University) ;
  • Yoo, Mi-Ae (Dept. of Molecular Biology, College of Natural Science, Pusan National University) ;
  • Lee, Won-Ho (Dept. of Biology, College of Natural Science, Pusan National University)
  • 발행 : 1995.12.01
PDF 다운로드
⟨ 이전 논문 다음 논문 ⟩

초록

In order to analyze the sex-linked lethal mutagenic effects of ethyl methanesulfonate (EMS) in Drosophila melanogaster, the mutagenicities from the attached-X and Basc method have been detected. The indexes of relative lethal mutations at 2.0 and 4.0mM EMS treated group using the attached-X method were about 1.5 and 2.4 times than that of 1.0mM treated group, respectively. EMS had more pronounced effect in the sperm and spermatid stages in the induction of X-linked lethal mutations during the spermatogenesis. And, in the induction of X-linked recessive lethal mutations from the Basc method, the mutation frequency of 4.0mM EMS treated group as compared with 2.0mM was more than three fold. Two assay systems used in this study can support mutually according to experimental purposes, and the area of its application can be considerably wide.

키워드

참고문헌

  1. Chemical mutagens v.2 The detection of mutations in Drosophila melanogaster Abrahamson,S.;E.B.Lewis;Hollander(ed.)
  2. J. Science v.45 Physiological genetic effects of HgCl₂in Drosophila melanogaster Choi,Y.H.;W.H.Lee
  3. J. Science v.47 Toxic and mutagenic effects of N-methyl-N'-nitro-N-nitrosoguanidine and ethidium bromide ih Drosophia melanogaster Choi,Y.H.;W.H.Lee
  4. J. Environ. Studies v.7 Comparative mutagenic effects of methyl methanesulfonate on the X, 2nd and 3rd chromosomes in Drosophila melanogaster Choi,Y.H.;Y.M.Lim;W.H.Lee
  5. J. Environ. Studies v.9 Comaparative studies on the toxicity of neoasozine in the Drosophila melanogaster subgroup Choi,Y.H.;W.H.Lee
  6. J. Korean Environ. Sci. Soc. v.1 no.2 Comparative toxic effests of gramoxone in the Drosophila melanogaster and its sibling species Choi,Y.H.;W.H.Lee;M.A.Yoo
  7. Mutat. Res. v.122 Comparative induction of somatic eye-color mutations and sex-linked recessive lethals in Drosophila melanogaster by tryptophan pyrolysates Fujikawa,K.;E.Inagaki;M.Uchibori;S.Kondo
  8. Jpn. J. Genet. v.56 Storage effects on sex-chromosome loses induced by triethylene melanine (TEM) and ethyl methanesulfonate (EMS) in Drosophila melanogaster Ikebuchi,M.;Y.Teranishi
  9. Jpn. J. Genet v.53 Toxicity and mutagenicity of cadmium and furylfuramide in Drosophila melanogaster Inoue,Y.;T.K.Watanabe
  10. 遺傳 v.34 農藥重金屬の 昆蟲に 與之る 影響 井上 寬
  11. 環境變異原硏究 v.5 ショウツョウハエに おける Basc法と 付着 X 法の 比較 井上 寬
  12. 環境變異原硏究 v.6 キイロツョウツョウハエを 用いた D-Dの 伴性 劣性 致死 試驗 井上 達生;稼本 令子;森谷 正明;白順 茶彦
  13. Am. Natur. v.104 Production and relative frequency of maternally influence lethals in Drosophila melanogaster Kaplan,W.D.;R.L.Seecof;W.E.Trout;M.E.Pasternack
  14. The genetics and biology of Drosophila v.1e Chemical mutagenesis Lee,E.R.;Ashburner(ed.);Ashburner(ed.)
  15. Drosophila Infor. Serv. v.43 Methods of feeding ethyl methanesulfonate (EMS) to Drosophila males Lewis,E.B.;F.Bacher
  16. Mutat. Res. The mutagenic effects of two monofunctional alkylating chemicals on mature spermatozoa of Drosophila Lim,J.K.;L.A.Snyder
  17. Carnegie Inst. Wash. Publ. no.627 Genetic variations of Drosophila melanogaster Lindsley,D.L.;E.H.Grell
  18. Mutat. Res. v.91 Mutagenicity of ethidium bromide in the sex-linked recessive lethal assay in Drosophila melanogaster Lopez de Sepulveda,J.L.;R.Marcos;N.Xamana;A.Creua
  19. Mutagenicity testing Mutation tests with the frui fly Drosophila melanogaster Mitchell,I.de G.;R.D.Combes;Venit(ed.);Parry(ed.)
  20. 培風館 ツョウツョウハエのの 遺博實習 森脇 大五郞
  21. 集團, 行動 遺博學 硏究法 大島 長造
  22. The genetics and biology of Drosophila v.1c Radiation genetics Sankaranarayan,K.;F.H.Sobels;Ashburner(ed.);Novitski(ed.)
  23. Mutat. Res. v.26 The advantages of Drosophila for mutation studies Sobels,F.H.
  24. Mutat. Res. v.92 A search for some common characteristics of the effects of chemical mutagens in Drosophila Vogel,E.W.;W.G.H.Blijleven;M.J.H.Kortselius;J.A.Zijlsyra
  25. Environmental mutagens and carcinogens Examing the mechanism of mutagenesis in DNA repair-deficient strains of Drosophila melanogaster Smith,P.D.;R.Dusenbery;S.F.Cooper;C.F.Baumen;Sugimura(ed.)(et al.)
  26. Jpn. J. Genet. v.48 Fertility genes in natural population for Drosophila melanogaster. Ⅱ. Correlation between productivity and viability Watanabe,T.K.;O.Oshima