Effects of Some Monoterpenes on Rat Brain Monoamine Oxidase

수종 모노테르펜계 화합물이 랫드 뇌의 monoamine oxidase활성에 미치는 영향

  • Published : 1995.12.01

Abstract

Eight natural or semistynthesized monoterpenes were examined for their effects in rat brain monoamine oxidase(MAO) using benzylamine as substrate. Thujone and 3-carene were found to have the inhibition effects on rat brain MAQ activity, 38% and 95% inhibition at 103M respectively. The kinetic study on 3-carene, the most potent inhibitive type. But (+) pulegon and (-) isopulegon was found to activate MAO slightly.

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