Journal of Microbiology

  • 제33권4호
  • /
  • Pages.322-327
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  • 1995
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  • 1225-8873(pISSN)
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  • 1976-3794(eISSN)
한국미생물학회 (The Microbiological Society of Korea)
권호 표지

Induction of ethanol tolerance on the production of 17-ketosteroids by mutant of mycobacterium sp.

  • Kim, Mal-Nam (Department of Biology, Sangmyung Womens University) ;
  • Kim, Eun-Mi (Department of Biology, Sangmyung Womens University)
  • 발행 : 1995.12.01
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초록

Tolerance of Mycobacterium sp. against organic solvents has been induced for the cholesterol side chain degradation by adding chemicals associated with synthesis of fatty acids or alcohols. Biotin of 300 .mu.g/1 and 0.5% aqueous ethanol solution were optima for the enhancement of ethanol tolerance of the microorganism. The induction of ethanol tolerance by biotin was found to be due to increase of degree of unsaturation of the fatty acids in membranous phospholipid of the cell, especially due to increase of oleic acid content. However when 0.5% of ethanol was added for the ethanol tolerance induction, there was an ambiguous correlation between ethanol tolerance and degree of unsaturation of the fatty acids, in spite of the fact that the induction increased the content of unsaturated fatty acids. Addition of 0.5% of ethanol induced several ethanol shock proteins having molecular weight similar to that of heat shock proteins.

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참고문헌

  1. Acyl lipid in photosynthetic system In Methods in Enzymology v.23 Allen,C.F.;P.Good
  2. Appl. Environ. Microbiol. v.60 Oxidative bioconversion of cholesterol by Pseudomonas sp. strain ST-200 in water-organic solvent two-phase system Aono,R.;N.Doukyu;H.Kobayashi;H.Nakajima;K.Horikoshi
  3. Enzyme Microb. Technol. v.9 Effect of Tween 80 and oleic acid on ligninase production by Phanerochaete chrysosporium INA-12 Asther,M.;G.Corrieu;R.Dvapron;E.Odier
  4. J. Gen. Microbiol. v.128 Production and tolerance of ethanol in relation to phospholipid fatty acyl composition in Sacchromyces cerevisiae NCYC 431 Beavan,M.J.;C.Charpentier;A.H.Rose
  5. Biotechnol. Bioeng. v.17 The enzymatic transformation of water-insoluble reactants in nonaqueous solvents. Conversion of cholesterol to cholest-4-ene-3-one by a Norcardia sp. Buckland,B.C.;P.Dunnill;M.D.Lilly
  6. J. Bacteriol. v.174 The response of a Baeillus subtilis temperature-sensitive sigA mutant to heat stress Chang,B.-Y.;K.-Y.Chen;Y.-D.Wer;C.-T.Liao
  7. Sodium dodecyl sulfate-polyacylamide gel electrophoresis for the separation and resolution of bacterial components In Methods in Practical Laboratory Bacteriology Chart,H.
  8. Enzyme Microb. Technol. v.9 Ethanol tolerance of yeast D'Amore,T.;G.G.Stewart
  9. Appl. Microbiol. Biotechnol. v.25 The effect of watermiscible solvents on the △ -dehydrogenase activity of free and PAAH-entrapped Arthrobacter simplex Freeman,A.;M.D.Lilly
  10. Enzyme Microbiol. Technol. v.11 Steroid transformation in aqueous two-phase systems: Side-chain degradation of cholesterol by Mycobacterium sp. Flygare,S.;P.-O.Larsson
  11. Biotechnol. Bioeng. v.11 Steroid transformation in aqueous two-phase systems: Side-chain degradation of cholesterol by Mycobacterium sp. Flygare,S.;P.-O.Larsson
  12. Biotechnol. Bioeng. v.25 Some effects of metal ions on the estimation of reducing sugars in biological media Forouhi,E.;D.J.Gunn
  13. Trends Biotechnol. v.12 Mechanisms behind resistance of whole cells to toxic organic solvents Heipieper,H.J.;F.J.Weber;J.Sikkema;H.Keweloh;J.A.M.de Bont
  14. Enzyme Microbiol. Technol. v.10 Stability of the steroid △¹-dehydrogenation system of Arthrobacter simplex Hocknull,M.D.;M.D.Lilly
  15. J. Bacteriol. v.125 Adaptation of membrane lipids to alcoholsss Ingram,L.O.
  16. Kor. J. Microbiol. v.30 Ethanol tolerance of Campylobacter jejuni Kim,C.K.;T.H.Ga
  17. Arch. Pharm. Res. v.3 Solvent effect of enzymatic steroid transformation Kim,D.H.;S.B.Lee;D.D.Y.Ryu
  18. Appl. Microbiol. v.23 Microbial degradation of sterols Marsheck,W.J.;S.Kraychy;R.D.Muir
  19. Appl. Microbiol. Biotechnol. v.30 Relationship between ethanol tolerance and fatty acyl composition of Saccharomyces cerevisiae Mishra,P.;R.Prasad
  20. Appl. Environ. Microbiol. v.54 Influence of calcium ion on ethanol tolerance of Saccharomyces bayanus and alcoholic fermentation by yeast Nabasi,R.C.;I.S.Correia;C.A.Viegas;J.M.Novais
  21. Annu. Rev. Genet. v.27 The function of heat-shock proteins in stress tolerance: Degradation and reactivation of damaged proteins Parsell,D.A.;S.Lindquiist
  22. Infect. Immunol. v.62 Heat shock response and heat shock protein antigens of Vibrio cholerae Sahu,G.K.;R.Chowdhury;J.Das
  23. J. Bacteriol. v.169 Differential induction of heat shock, SOS and oxidation stress regulons and accumulation of nucleotides in Escherichia coli VanBogelen,R.A.;P.M.Kelley;F.C.Neidhardt
  24. Biochem. Biophys. Acta. v.531 Bioconversion of sitosterol to useful steroidal intermediates by mutants of Mycobacterium fortuitum Wovcha,M.G.;F.J.Antosz;J.C.Knight;L.A.Kominek;T.R.Pyke