The Liver Protective Activities of Some Iranian Medicinal Plants Against Liver Damage in Mice Induced by $CCL_4$ Intoxication

  • Kalantari. H. (School of Pharmacy, Ahwaz University of Medical Sciences and Health Services) ;
  • Aghel. N. (School of Pharmacy, Ahwaz University of Medical Sciences and Health Services) ;
  • Annafecheh. M. (School of Pharmacy, Ahwaz University of Medical Sciences and Health Services) ;
  • Mar, Woong-Chon (Natural Products Research Institute, Seoul National University) ;
  • Chang, Il-Moo (Natural Products Research Institute, Seoul National University)
  • 발행 : 1995.12.01

초록

The aim and objective of this study are to carry out the liver protective activities against the $CCl_4$ intoxication in mice with some Iranian medicinal plants traditionally used for liver injuries. The methanol extracts of Cichorium intybus, Lactuca scarJoia, Eucalyptus camadulensis were evaluated. With various doses of these plants, liver protective activities were performed after $CCl_4$ administration to mice. The serum aminotransferases activites, liver sizes, and histopatological examinations of liver were studied. At a dose of 50 mg/ kg, all three plants were able to protect liver damages induced by $CCl_4$.

키워드

참고문헌

  1. J. Med. Plant Res. v.49 Yoshinobu,K.;Masahiro,T.;Hiroshi,H.
  2. Kor. J. Pharmacol v.9 Chang, II-Moo;Yun Hye Sook
  3. Martindale Extrapharmacopoeia. 29th ed. Reynolds,E.F.
  4. Iranian Medicinal Plants Amin,G.H.
  5. Introduction to Medicinal Plants Prescription,5th ed. samsam Shariat,H.;Moatar,F.
  6. Medicinal Plant. 2nd ed Tavakoli Saberi,M.;Sedaght,M.
  7. Medicinal Plants. Third ed. Zargar,A.
  8. Kor. J. Pharmacogn. v.10 Chang, II-Moo;Yun Choi; Hye Sook
  9. Kor. J. Pharmacong. v.20 Chang, II-Moo et al