Toxicological Research

  • 제11권2호
  • /
  • Pages.223-227
  • /
  • 1995
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  • 1976-8257(pISSN)
  • /
  • 2234-2753(eISSN)
한국독성학회 (Korean Society of Toxicology & Korea Environmental Mutagen Society)
권호 표지

한국산 생약으로부터 해독물질의 개발(제2보) 흰쥐 간장내의 카드뮴 축적에 미치는 금은화 추출물의 영향

Development of Antitoxic Agents from Korean Medicinal Plants. Part 2. Effects of Lonicerae flos Extract on the Accumulation of Cadmium in Liver

  • 백승화 (원광대학교 자연과학대학 화학과) ;
  • 유일수 (이리농공전문대학 화공과) ;
  • 이종섭 (원광대학교 의과대학 예방의학교실) ;
  • 한두석 (원광대학교 치과대학 구강해부학교실)
  • 발행 : 1995.12.01
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초록

This study was conducted to investigate the metallothionein (MT) induction by Lonicerae rios in cadmium chloride intoxication. The results were as follows: Generally, detoxication effects by Lonicerae fios extract increased to the increase of extract concentrations. When 90 mg/kg dosage of Lonicerae fios extract was administered, it showed the highest antitoxic effects in metallothionein induction. From the above results, Lonicerae rios extract increased metallothionein concentration and decreased the toxicity of cadmium in liver.

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참고문헌

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