Journal of Photoscience

Korean Society of Photoscience (한국광과학회)
권호 표지

THE EFFECTS OF ZINC DURING VISUAL ADAPTATION OF VERTEBRATE EYE

  • Kim, Hyun-Jung (Department of Biochemistry, College of Natural Sciences, Kyungpook National University)
  • Published : 1995.06.01
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Abstract

Zinc plays a key role in genetic expression, cell division, and growth and is essential for the function of more than 200 enzymes; effects of zinc deficiency induce many syndromes, including abnormal visual adaptation. The pigment epithelium (EP) contains high concentrations of zinc in humans and in animals and it participates in threshold elevation, visual sensitivity increment, and acceleration of rhodopsin regeration during visual adaptation. The origin of c-wave of electroretinogram(ERG) is not only pigment epithelium as shown in present research, but also other cell layers, perhaps the photoreceptors. We propose zinc as a candidate for an internal messenger which participates in signal amplification.

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References

  1. Ann. Rev. Pharmacolo. toxicol v.20 Clinical, Biochemical and Pharmacological role of zinc Prasad,A.S.
  2. Cell v.51 Isolation of cDNA encoding transcription factor Sp1 and functional analysis of the DNA binding domain Kadonaga,J.T.;K.P.Carner;F.R.Masiarz;R.Tjion
  3. J. Biol. Chem v.262 The binding activity of estrogen receptor to DNA and heat shock protein in dependent on receptorbound metal Sabbah,M.;G.Redeuilh;C.Secco;E.E.Baulieu
  4. Biochemistry v.15 Euglena gracilis DNA-dependent RNA polymerase Ⅱ: A zinc metalloenzyme Falchuck;K.H.;B.Mazus;L.Ulpino;B.L.Vallee
  5. Nature v.328 Genetic evidence that zinc is an essential co-factor in the DNA binding domain of GAL4 protein Jhonson,M.
  6. EMBO J v.7 A zinc responsive factor interacts with a metal-regulated enhancer element (MRE) of the mouse metallothionein-1 gene Westin,G.;W.Schaffner
  7. J. Lab. Clin. Med v.61 Zinc metabolism in patients with the syndrome of iron deficiency anemia, hepatosplenomegaly, dwarfism, and hypoponadism Prasad,A.S.;A.Miale;Z.Farid;H.H.Sanstead;A.R.Schulert
  8. Disorders of mineral metabolism v.2 Zinc in human nutrition Sandstead,H.H.Bronner,F.(ed.);J.Coburn(ed.)
  9. Nutrition v.9 Zinc deficiency in elderly Patients Prasad,A.;J.Fitzgerald
  10. Linear growth retardation in less development countries The epidemiology of stunting Keller,W.;Waterlow,J.(ed.)
  11. Ann. J. Clin. Nutr v.53 Growth in children from the wosera subdistrict, Papus New Guinea, in relation to energy and protein intakes and zinc status Gibson,R.;A.Heywood;C.Yaman;P.Heywood
  12. Ann. J. Clin. Nutr v.49 A growth-limiting, mild zinc-deficiency syndrome in some Southern Ontario boys with low height percentiles Gibson,R.;A.MacDonald;A.Goldman;A.Berry
  13. An. J. Physiol v.230 Function of pituitaryionadal axis in zinc-deficient rats Lei,K.Y.;A.Abbais
  14. Nutr. Rev v.32 Vitamin A deficiency, rerophthalmia and blindness Oomen,H.A.P.C.
  15. Brain Res v.50 Dark adaptation slowed by inhibitor of alcohol dehydrogenase in the albino-rat Roskin,N.H.;K.P,Sligar;R.Steinberg
  16. J. Nutr v.105 Effects of zinc deficiency on the oxidation of retinol and ethanol in rats Huber,A.M.;S.N.Gershoff
  17. Nutr. Rep. Int v.25 Effect of zinc supplementation on retinol reductase in zinc deficient rats Cossack,Z.T.;A.S.Prasad;D.Konuich
  18. Report Number 1. USAF School of Aviation Medicine Studies on the electrophysiology and the metabolism of the retina Noell,W.K.
  19. J. Gen. Physiol v.56 Visual adaptation is the retina of the skate Dowling,J.E.;H.A.Ripps
  20. J. Gen. Physiol v.60 Adaptation in skate photoreceptor Dowling,J.E.;H.Ripps
  21. Nature v.188 Chemistry of visual adaptation in the rat Dowling,J.E.
  22. J. Gen. Physiol v.46 Neural and photochemical mechanism of visual adaptation in the rat Dowling,J.E.
  23. J. Physiol v.156 Dark adaptation and the regeneration of rhodopsin Rushton,W.H.A.