YAKHAK HOEJI (약학회지)

The Pharmaceutical Society of Korea (대한약학회)
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Screening of the Inhibiory Effects of Herbal Medicines on the Platelet Activating Facthr(PAP) Binding : Randomly Selected Herbal Medicines

생약 물 추출물의 혈소판 활성화 인자결합 억제효과 검색 : 무작위로 선정한 국내 유통 생약

  • 한병훈 (서울대학교 천연물과학연구소) ;
  • 양현옥 (서울대학교 천연물과학연구소) ;
  • 이승룡 (일양약품 중앙연구소) ;
  • 조순현 (일양약품 중앙연구소) ;
  • 고현정 (서울대학교 천연물과학연구소) ;
  • 한용남 (서울대학교 천연물과학연구소)
  • Published : 1995.02.01
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Abstract

As a continuation of the previous study, a second group of sixty two aqueous extracts(freeze dried) from natural products was screened for the inhibitory effect of platelet activating factor(PAF) binding to rabbit platelet using 0.6 nM [$^{3}$H]PAF as a radioligand. The results demonstrated that three medicinal plants inhibited 40~50% of [$^{3}$H]PAF equilibrium binding at the concentration of 200 $\mu\textrm{g}$/ml.

Keywords

References

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