Archives of Pharmacal Research
- Volume 18 Issue 2
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- Pages.133-135
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- 1995
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- 0253-6269(pISSN)
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- 1976-3786(eISSN)
Anti-inflammatory Activity of the Major Constituents of Lonicera japonica
- Lee, Song-Jin (College of Pharmacy, Kangweon National University) ;
- Shin, Eun-Joo (Dept. Food Nutr, Andong Natl University) ;
- Son, Kun-Ho (Dept. Food Nutr, Andong Natl University) ;
- Chang, Hyeun-Wook (College of Pharmacy, Yengnam University) ;
- Kang, Sam-Sik (Natural Products Research Institute, Seoul National University) ;
- Kim, Hyun-Pyo (College of Pharmacy, Kangweon National University)
- Published : 1995.04.01
Abstract
Previously, we reported that the n-butanol fraction of Lonicera japonica showed anti-flammatory activity in mice and rats. Several constituents such a loniceroside A and B, flavonoids and iridoids were isolated from this fraction. In this investigation, the anti-inflammatory activity of the major constituents of L. japonica was studied. Loniceroside A, lonicerin and loganin showed anti-inflammatory activity comparable to aspirin.
Keywords
- Lonicera Japonica;
- n-butanol fraction;
- Anti-inflammatory activity;
- Loniceroside A;
- Lonicerine;
- Loganin