BMB Reports
- 제28권4호
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- Pages.290-292
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- 1995
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- 1976-670X(eISSN)
Hydrophobic Interaction Between the Acyl Moiety of Choline Esters and the Active Site of Acetylcholinesterase
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Myung, Pyung-Keun
(Department of Pharmacy, College of Pharmacy, Chungnam National University) ;
- Sok, Dai-Eun (ARTC #6-7, Agency for Defense Development)
- 발행 : 1995.07.31
초록
Existence of a binding site for choline esters with an acyl chain of various sizes was examined by comparing the inhibitory potency of the respective compound. In contrast to acetylcholine, which showed a pure competitive pattern of inhibition, choline esters with an acyl chain of a long size (