대한치과교정학회지 (The korean journal of orthodontics)
- 제25권6호
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- Pages.723-731
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- 1995
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- 2234-7518(pISSN)
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- 2005-372X(eISSN)
A STUDY ON THE EXPRESSION OF TYPE I AND TYPE II COLLAGEN GENES AND PROTEINS IN THE DEVELOPING HUMAN MANDIBLE
- Kook, Yoon-Ah (Department of Orthodontics, College of Dentistry, WonKwang University) ;
- Kim, Sang-Cheol ;
- Kim, Eun-Cheol
- 발행 : 1995.12.01
초록
Type I and type II collagens are considered the major collagens of bone and cartilage respectively. Monitoring the patterns of those gene and protein expressions during development will provide a basis for the understanding of the normal and abnormal growths. This study was undertaken to investigate the expression of collagen genes and proteins involved in the developing human mandible. Fifty embryos and fetuses were studied with Alcian blue-PAS, Masson's Trichrome, reverse transcription polymerase chain reaction (RT-PCR), Western blot analysis, and Southern blot analysis. Our results showed that