마두령(馬兜鈴)의 흰쥐 간염(肝炎) 억제(抑制) 효과(效果)에 관(關)한 실험적(實驗的) 연구(硏究)

Inhibitory effects of Maduryung(Aristolochiae Fructus) on alcohol, acetaminophen and galactosamine induced hepatitis in rats

  • 발행 : 1995.12.05

초록

Maduryung Extract, one of herbal medicine was tested for inhibitory effect to alcohol, acetaminophen and d-galactosamine induced hepatitis in rats. The results were as follows. 1. Increaced serum GOT, GPT levels by alcohol were significantly decreased by Maduryung extract.(p<0.01) 2. Maduryung extract decreaced GOT value in acetaminophen induced hepatitis and this effect may be due to increace of GSH level in liver tissue.(p<0.05) 3. Repeat administration of Maduryung extract showed inhibitory effect on s-GOT, s-GPT levels in d-galactosamine induced hepatitis. (p<0.05) According to the above results, it seems that Maduryung could be use as drug for alcohol or drug induced hepatitis treatment.

키워드

참고문헌

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