Korean Journal of Pharmacognosy (생약학회지)
- Volume 26 Issue 2
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- Pages.116-121
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- 1995
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- 0253-3073(pISSN)
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- 2288-9299(eISSN)
Analysis of Taxol and Cephalomannine in Cheju Island Yew (Taxus cuspidata S. et Z.)
제주도 주목(Taxus cuspidata S. et Z.)의 Taxol 및 Cephalomannine의 함량분석
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Kwak, Sang-Soo
(Bioresources Research Group, Korea Research Institute of Bioscience and Biotechnology, KIST) ;
- Choi, Myung-Suk (Department of Forestry, Kyungpook National University) ;
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Park, Young-Goo
(Department of Forestry, Kyungpook National University) ;
- Ko, Kyung-Soo (Development & Research Team, Hankook Shin Yak Pharm. Co., LTD.) ;
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Liu, Jang-Ryol
(Bioresources Research Group, Korea Research Institute of Bioscience and Biotechnology, KIST)
-
곽상수
(KIST 생명공학연구소 생물자원연구그룹) ;
- 최명석 (경북대학교 임학과) ;
-
박용구
(경북대학교 임학과) ;
- 고경수 ((주) 한국신약 개발연구실) ;
-
유장렬
(KIST 생명공학연구소 생물자원연구그룹)
- Published : 1995.06.30
Abstract
To seek for a stable supply source of taxol as an anticancer agent urgently needed for the treatment of ovarian cancer, the concentrations of taxol and cephalomannine in bark and needles of 37 yew (Taxus cuspidata S. et Z.) trees grown in 6 locations of Cheju Island were analyzed by using HPLC. A considerable variation in the content was observed in plant part and the location. The average taxol content in the needles (