생약학회지 (Korean Journal of Pharmacognosy)
- 제26권2호
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- Pages.154-158
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- 1995
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- 0253-3073(pISSN)
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- 2288-9299(eISSN)
수종 생약의 항혈전활성
Antithrombotic Effects of Some Traditional Plant Medicines
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YunChoi, Hye-Sook
(Natural Products Research Institute, Seoul National University) ;
- Chung, Kyo-Soon (Natural Products Research Institute, Seoul National University) ;
- Kim, Moon-Hee (Natural Products Research Institute, Seoul National University) ;
- Oh, Jay-Hee (Natural Products Research Institute, Seoul National University)
- 발행 : 1995.06.30
초록
Twentyfive plant crude drugs with traditional reputation were selected for the antithrombotic screening. MeOH (80%) extract of each plant was given (500 mg/Kg, p.o.) to mice 1 hr prior to the thrombotic challenge (1.8 mg collagen plus 180 ug epinephrine/Kg, i.v.). Seven extracts (1, 2, 8, 10, 18, 22 and 23) showed either comparable or better recovery than aspirin (50 mg/Kg, p.o.) from paralysis caused by the pulmonary thrombosis. 1, 2, 8, 10, 18, 22 and 23 were fractionated to