Sleep Medicine and Psychophysiology (수면정신생리)

KOREAN ACADEMY OF SLEEP MEDICINE (대한수면의학회)
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Therapeutic Change of Sleep Structure and Function by Continuous Positive Airway Pressure Application in Obstructive Sleep Apnea Syndrome

폐쇄성(閉鎖性) 수면(睡眠) 무호흡증(無呼吸症)에서 지속적(持續的) 상기도(上氣道) 양압술(陽壓術)에 따른 수면구조(睡眠構造) 및 기능(機能) 변화(變化)

  • Jeong, Do-Un (Department of Psychiatry, Seoul National University College of Medicine and Division of Sleep Studies, Seoul National University Hospital) ;
  • Yoon, In-Young (Department of Neuropsychiatry, Seoul National University Hospital) ;
  • Shim, Young-Soo (Department of Internal Medicine, Seoul National University College of Medicine)
  • 정도언 (서울대학교 의과대학 정신과학교실 및 서울대학교병원 수면다원검사실) ;
  • 윤인영 (서울대학교병원 신경정신과) ;
  • 심영수 (서울대학교 의과대학 내과학교실)
  • Published : 1994.12.31
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Abstract

Obstructive sleep apnea syndrome(OSAS) is most frequently diagnosed in the sleep laboratories and its severity is objectively estimated. In terms of treatment, the most prevalent method is the continuous positive airway pressure(CPAP) application as of now. However, in Korea, CPAP is still not sufficiently known and it is attributable to the fact that sleep study facilities have not been popularized. In this article, the authors present their own experience with CPAP in nine subjects with OSAS. In this study, CPAP was found to decrease stage 1 sleep and to increase stage 2 sleep, with increasing mean oxygen saturation and decreasing lowest oxygen saturation during nocturnal sleep. Also, it tended to increase sleep continuity and generally to improve sleep architecture. Rebound slow wave and/or REM sleep stages during CPAP were also noted in 8 out of 9 cases. The authors suggest that CPAP should be considered as the primary mode of treatment for patients with obstructive sleep apnea syndrome and related educational programs for physicians should be developed and provided by sleep specialists.

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