The Korean Journal of Nuclear Medicine (대한핵의학회지)

The Korean Society of Nuclear Medicine (대한핵의학회)
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Is $^{201}Tl-^{99m}Tc$-Subtraction Scan an Accurate Diagnostic Method to Detect Parathyroid Mass?

$^{201}Tl/^{99m}Tc$ 감영스캔으로 부갑상선종괴를 얼마나 찾을 수 있는가?

  • Yang, Hyung-In (Division of Nuclear Medicine, Endocrinology, Department of Internal Medicine, Kyung Hee University School of Medicine) ;
  • Kim, Deog-Yoon (Division of Nuclear Medicine, Endocrinology, Department of Internal Medicine, Kyung Hee University School of Medicine) ;
  • Kim, Kwang-Won (Division of Nuclear Medicine, Endocrinology, Department of Internal Medicine, Kyung Hee University School of Medicine) ;
  • Choi, Young-Kil (Division of Nuclear Medicine, Endocrinology, Department of Internal Medicine, Kyung Hee University School of Medicine)
  • 양형인 (경희대학교 의과대학 내과학교실) ;
  • 김덕윤 (경희대학교 의과대학 내과학교실) ;
  • 김광원 (경희대학교 의과대학 내과학교실) ;
  • 최영길 (경희대학교 의과대학 내과학교실)
  • Published : 1994.05.15
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Abstract

We studied 65 patients with hypercalcemia who had heed performed $^{201}Tl/^{99m}Tc$ subtraction scan, 21 of them were confirmed as parathyroid tumor (19 adenoma, 2 carcinoma). The diagnostic sensitivity of $^{201}Tl/^{99m}Tc$ subfraction scan for detecting parathyroid mass was 90.5%, specificity was 97.6%, ultrasonography was 80.6%, 58.8%, respectively. The causes of two false negative cases were relatively small size ($1.5{\times}1{\times}0.8cm$) compared to remainig cases and poor thallium uptake due to cystic necrosis of parathyroid adenoma. The one false positive case was non-functioning thyroid nodule. $^{201}Tl/^{99m}Tc$ subtraction scan was simple, effective diagnostic tool and superior to ultrasonography for evaluating the parathyroid mass with high sensitivity and specificity.

$^{201}Tl-^{99m}Tc$ 감영스캔이 시행되었던 65명의 환자에서 $^{201}Tl-^{99m}Tc$ 감영스캔의 진단적 가치와 위 음성과 위 양성의 원인에 대해 조사하였다. 이들 중 21예가 부갑상선선종으로 확진되었고, 이들에서 $^{201}Tl-^{99m}Tc$ 감영스캔의 예민도는 90.5%, 특이도는 97.6%였다. 위 음성을 보인 예는 낭종성 괴사를 보인 부갑상선선종과 크기가 $1.5{\times}1{\times}0.8 cm$ 정도로 작은 종양이었다. 위 양성을 보인 1예는 무 기능성 갑상선종이었다. 결론적으로 $^{201}Tl-^{99m}Tc$ 감영스캔은 부갑상선 종괴를 찾아내는데 특이도와 예민도가 높은 검사로 생각된다.

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