Journal of Food Hygiene and Safety (한국식품위생안전성학회지)
- Volume 9 Issue 1
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- Pages.15-21
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- 1994
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- 1229-1153(pISSN)
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- 2465-9223(eISSN)
Comparative Study on the Mutagenic Activity of Phenothiazines by UV-A Irradiations
UV-A 조사에 의한 Phenothiazines의 돌연변이원성 비교 연구
Abstract
The mutagenic activity of four phenothiazine derivatives such as chlorpromazine, perphenazine, trifluoperazine and thioridazine in conjunction with UV-A irradiation or not based on the Ames plate incorporation test in the presence and absence of liver microsomal enzyme(S9 fraction). None of these compounds and their photo-excited were detected as mutagen in the Salmonella microsome assay with TA 98 and TA 100.