Archives of Pharmacal Research
- Volume 17 Issue 5
- /
- Pages.375-377
- /
- 1994
- /
- 0253-6269(pISSN)
- /
- 1976-3786(eISSN)
Antitumor Triterpense from Medicinal Plants
-
Ryu, Shi-Yong
(Korea Research Institute of Chemical Technology)
;
-
Choi, Sang-Un
(Korea Research Institute of Chemical Technology)
;
- Lee, Seung-Ho (Korea Research Institute of Chemical Technology) ;
-
Lee, Chong-Ock
(Korea Research Institute of Chemical Technology)
;
- No, Zaesung (Korea Research Institute of Chemical Technology) ;
- Ahn, Jong-Woong (Korea Research Institute of Chemical Technology)
- Published : 1994.10.01
Abstract
Thirteen kinds of naturally occurring or derivatised thiterpenes, reported to have an antitumoral property, were reinvestigated on the basis of their direct cytotoxicity or the inhibitory activity on cell growth against five kinds of cultured human tumor cells, i.e., A-549, SK-OV-3, SK-MEL-2, XF-498 and HCT15, in vitro. Ursonic acid III, betulinic acid VIII, betulonic acid X and glycrrhetinic acid XI were exhibitied a marked inhibition on cell growth.