Archives of Pharmacal Research
- Volume 17 Issue 4
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- Pages.278-280
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- 1994
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- 0253-6269(pISSN)
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- 1976-3786(eISSN)
Synthesis of Some New 4H-(Pyrano and/or Piperidino)[3,2-d] Pyazoles and Pyrazolo[5,4-d] Thiopyrans
- Etman, H.A. (Department of Chemistry, Faculty of Science, University of Mansoura) ;
- El-Ahl, A.S. (Department of Chemistry, Faculty of Science, University of Mansoura) ;
- Metwally, M.A. (Department of Chemistry, Faculty of Science, University of Mansoura)
- Published : 1994.08.01
Abstract
1,5-diketones(3) undewent cyclization to 4H-pyrano[3,2-d]pyrazoles (4a-d),4H-piperidino[3, 2-d]pyrazole (5) and pyrazolo[5,4-d]thiopyran (6) upon treatment with P/sub 2/O/sub 5/, CH/sub 3/COONH/sub 4/ and /or P/sub 2/S/sub 5/. Moreover, treatment of (4) with CH/sub 3/COONH/sub 4/ and/or P/sub 2/S/sub 5/ afforded (5) and (6). The structures of the hitherto unknown ring systems have been confirmed by analytical and spectral data.