The Experimental Studies on the Effects of Kunlitang

건리탕(建理湯)의 효능(效能)에 대(對)한 실험적(實驗的) 연구(硏究)

  • 임선빈 (대전대학교 한의과대학 내과학교실) ;
  • 김병탁 (대전대학교 한의과대학 내과학교실)
  • Published : 1994.08.31

Abstract

KUNLITANG(建理湯) have been widely used in the disease of digestive system, which was based on the oriental references. In order to investigate the clinical effect of it, the experimental works were carried out with mice and rats. The following results have been obtained : 1. The analgesic effect in mice was recognized in acetic acid method. 2. The inhibitory effect on transfortation activity in small intestine of mice was recognized. 3. In the experiment to see the effects of KUNLITANG on the gastric juice in rats, volumn, free HCL and total acidity were decreased, pepsin activity was inhibited. Whi1e pH was increased by the administration of KUNLITANG, respectably. 4. In the experiment to see the effects of KUNLITANG on the gastric ulcers in rats, anti-ulcerative effects were recognized in Shay rats and induced by histamine or aspirine. 5. Spontaneous contraction in the isolated ileum in rats was inhibited. According to the above experimental results, it can be concluded that KUNLITANG are very effective on many gastrointestinal diseases of biwihehanheung(脾胃虛寒型)

Keywords

References

  1. 方藥合編 黃道淵
  2. 方劑學 尹吉永
  3. 方劑學 上海中醫學院
  4. 方劑學 李尙仁 외
  5. 仲景全書 張機
  6. 丹溪心法附餘 方廣(編)
  7. 增補萬病回春 공廷賢
  8. 醫學入門 李 정
  9. 醫方集解 汪 昻
  10. 景岳全書 張介賓
  11. 東醫寶鑑 許 浚
  12. 醫門寶鑑 周命新
  13. 後世處方解說 朴鍾甲(譯)
  14. 傷寒論譯註 蔡仁植
  15. 臟腑辨證論治 金完熙 외
  16. 東醫脾系內科學 朴鎬湜 외
  17. 實用中醫內科學 方葯中 외
  18. 理中湯煎劑가 家兎 摘出腸管에 미치는 效能에 關한 實驗的 硏究 崔晩休
  19. 大韓韓醫學會誌 v.5 no.1 理中湯 水鍼이 鎭痛 항사하 및 uropepsin치에 미치는 影響 高敬錫
  20. 圓光大學位論文集 v.4 理中湯煎湯液이 家兎의 胃運動에 미치는 影響 裵成達
  21. 慶熙韓醫大論文集 v.10 理中湯과 大承氣湯의 效能에 關한 實驗的 硏究 郭基煥
  22. 慶熙大 碩士學位論文 桂技湯, 桂技加桂湯, 小建中湯의 實驗的 硏究 여대원
  23. Brit. J. pharmac. Chemother. v.32 The use of changes in capillary permeability in mice to distinguish between narcotic and nonnarcotic analgesics Whittle, B.A.
  24. 日藥學雜誌 v.101 石井康子 외
  25. 日生藥學雜誌 v.36 加藤定秀 외
  26. 日應用藥理 v.21 桴井眞夫 외
  27. J. Gem. physiol. v.21 The estimation of pepsin, trypsin, papain and cathepsin with hemoglobin Anson, M.L.
  28. Method of enzymatic analysis v.1 Bergmeyer, H.V.
  29. gastroenterology v.5 A simple method for the uniform production of gastric ulceration in the rat. Shay, H.;Komarov, S.A.;Fcls, S.S.;Meranze, D.;Gruenstein, M. Siplet, H.
  30. 日藥學雜誌 v.103 no.4 生藥の 基源 修治 · 品質に關する硏究(第一報) 久保道德;野上眞理;西村おゆみ;森浦俊次;有地 滋
  31. Arch. Int. Pharmacodyn. v.143 Adami, E.;Marrazzi-Uberti, E.;Turba, C.
  32. 應用物理 v.24 no.5 岡部進;竹內孝治;石原安信;國見春代
  33. 藥物學實驗 高木敬次郞;小澤光
  34. 現代方劑學 金賢濟;金光湖(編)
  35. 神農本草經 孫星衍 輯
  36. 本草三家合註 張隱庵 외
  37. 本草綱目 李時珍
  38. 本草學 李尙仁
  39. 漢藥臨床應用 李尙仁
  40. Brite. J. phamac. Chemother. v.40 The abdominal constriction response and its suppression by analgesic drug in the mouse Collier, H.O.J.;Dinneen, L.C.;Johmson, Christine A.;Schneider, C.
  41. 內科學 이문호 외
  42. 生理學 이병희
  43. 慶熙大學校 大學院 博士學位論文 丹蔘補血湯 및 保和丸이 胃潰瘍에 미치는 影響 朴東源
  44. 生藥誌 v.28 生藥의 生物活性成分に關する硏究(第一報), 生藥의 抗潰瘍作用 山原修二;金眞理子;澤田德之助;騰村一
  45. 藥學雜誌 v.97 生藥の 生物活性成分に關する硏究, 朮の 藥理學的 品質評價 山原修二;澤田德之修;谿忠人;西野降雄;北川 東;騰村 一
  46. Japanese Journal of Pharmacology v.21 The Therapeutic Effect of FM 100., A Fraction of Licorice Root, on Acetic acid Ulcer in Rats. Takagi, K.(et al.)
  47. Arzneimittel Forschung v.17 Peptic Ulcer Inhibiting Properties of a New Fraction from Licorice Root(FM 100), I Exeperimental peptic Ulcer and General Pharmacology Takagi, K.;Ishii, Y.
  48. 藥學雜誌 v.104 no.5 藥用人蔘의 藥理學的 硏究(第二報) 松田秀秋;久保道德