The Journal of Korean Medicine (대한한의학회지)

The Society of Korean Medicine (대한한의학회)
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An experimental research of the effect of Gamichunggantang

가미청간탕(加味淸肝湯)의 효능(效能)에 관(關)한 실험적(實驗的) 연구(硏究)

  • Hong, Sang-Hun (Dept. of Oriental Internal Medicine, college of Oriental Medicine, Kyung Hee University) ;
  • Lee, Jang-Hun (Dept. of Oriental Internal Medicine, college of Oriental Medicine, Kyung Hee University) ;
  • Woo, Hong-Jung (Dept. of Oriental Internal Medicine, college of Oriental Medicine, Kyung Hee University) ;
  • Kim, Byung-Woon (Dept. of Oriental Internal Medicine, college of Oriental Medicine, Kyung Hee University)
  • 홍상훈 (경희대학교 한의과대학 간계내과학교실) ;
  • 이장훈 (경희대학교 한의과대학 간계내과학교실) ;
  • 우홍정 (경희대학교 한의과대학 간계내과학교실) ;
  • 김병운 (경희대학교 한의과대학 간계내과학교실)
  • Published : 1994.10.23
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Abstract

This study was performed to evaluate the effect of the Gamichunggantang on recovering from liver injury induced by d-galactosamine and ${\alpha}$-naphthylisothiocyanate. and following results were obtained. 1. The increases of the serum GOT. GPT activities in mice induced by d-galactosamine and ${\alpha}$-naphthylisothiocyanate were inhibited significantly by the administration of the Gamichunggantang. 2. The increases of the total cholesterol. triglyceride and blood urea nitrogen levels in mice induced by d-galactosamine and ${\alpha}$-naphthylisothiocyanate were significantly inhibited by the administration of the Gamichunggantang. 3. The increase of the ALP activity in mice following liver injury induced by d-galactosamine and ${\alpha}$-naphthylisothiocyanate were inhibited to an extend. but it was not significant. 4. It is considered that the efficacy of the Gamichunggantang on liver cell injury depends on its concentration rate.

Keywords

References

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