Journal of Pharmaceutical Investigation
- 제24권3호spc1호
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- Pages.67-77
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- 1994
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- 2093-5552(pISSN)
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- 2093-6214(eISSN)
Application of Experimental Design to Optimize Vitamin C-90 Tabletting Performance
초록
The RMS statistical approach has demonstrated its potential in developing pharmaceutical dosage forms and in improving tabletting performance. Using an optimized formula, the tabletting performances of vitamin C-90 such as compressibility, disintegration time, lubrication and friability are significantly enhanced when compared with the performance of a traditional test formula. More important, this method also enables us to serve our customers better. Any customized modification of a suggested formula or any technical problem related performance etc. can be readily resolved by simple examination of the models.