Korean Journal of Pharmacognosy (생약학회지)

The Korean Society of Pharmacognosy (한국생약학회)
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Coumarins from the Roots of Angelica decursiva-albiflora

개바디 뿌리의 쿠마린성분

  • 정남일 (경희대학교 약학대학) ;
  • 육창수 (경희대학교 약학대학) ;
  • 이형규 (한국과학기술연구원 유전공학연구소)
  • Published : 1994.12.31
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Abstract

From the root of Angelica decursiva-albiflora Yook, which has been used as a folk medicine for a sedative, analgesic and expectorant, four free coumarins, e.g., decursidin(I), decursin(II), umbelliferone(III) and nodakenetin(IV), and two coumarin glycosides, e.g., nodakenin(V) and decuroside I(VI) were isolate. The cytotoxicity of nodakenin(V) against L-1210 leukemia cells was less effective than cisplatin, but in the nephrotoxicity against rabbit kidney proximal tubular cell nodakenin(V) showed remarkably less nephrotoxicant than cisplatin.

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