Korean Journal of Pharmacognosy (생약학회지)
- Volume 25 Issue 1
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- Pages.47-50
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- 1994
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- 0253-3073(pISSN)
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- 2288-9299(eISSN)
Studies on the Biologic Activities of the Constituents of Ailanthi Cortex Radicis(I) -Effects of Methanol Extract and its Chloroform Fraction on Epoxide Hydrolyzing System in Liver-
저근백피(樗根白皮) 성분(成分)의 생리생활(生理生活)에 관한 연구(硏究)(I) -메탄올 추출물과 클로로포름 분획이 Epoxide 분해계에 미치는 영향-
- Kim, Jong (College of Pharmacy, Kyungsung University) ;
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Choi, Jong-Won
(College of Pharmacy, Kyungsung University) ;
- Kim, Hye-Kyung (College of Pharmacy, Kyungsung University) ;
- Park, Soo-Wan (College of Pharmacy,Kyungsung University) ;
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Lee, Chung-Kyu
(College of Pharmacy,Kyungsung University)
- Published : 1994.03.30
Abstract
For the biological survey, effects of Ailanthi Cortex Radicis, the root bark of Ailanthus altissima(Simaroubaceae) on epoxide hydrolyzing enzymes were checked. The methanolic extract and its chloroform fraction were shown to activate the liver metabolizing enzyme system including epoxide hydrolase system which was monitored by activities of transaminase, lactate dehydrogenase, alkaline phosphatase and epoxide hydrolase system in bromobenzene treated rats. But they showed no effect on glutathione S-transferase activity.
Keywords
- Ailanthi Cortex Radicis;
- Ailanthus altissima;
- Simaroubaceae;
- liver enzyme activity;
- epoxide hydrolase activity