The Journal of Dong Guk Oriental Medicine (동국한의학연구소논문집)

Research Institute of Oriental Medicine (동국대학교 한의학연구소)
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The Effects of Panax gineseng on the Side Effects of Cyclophosphamide to the Spleen in the Rat

인삼추출물이 Cyclophosphamide에 손상된 흰쥐 비장조직의 회복에 미치는 영향

  • Kim, Jin-Taek (Department of Pathology, Oriental Medical College, Dongguk University) ;
  • Kim, Dong-Hoan (Department of Pathology, Oriental Medical College, Dongguk University) ;
  • Ann, Sang-Hyun (Department of Pathology, Oriental Medical College, Dongguk University) ;
  • Yoon, Sik (Department of Anatomy, Medical College, Pusan National University)
  • 김진택 (동국대학교 한의과대학 해부학교실) ;
  • 김동환 (동국대학교 한의과대학 해부학교실) ;
  • 안상현 (동국대학교 한의과대학 해부학교실) ;
  • 윤식 (부산대학교 의과대학 해부학교실)
  • Published : 1993.03.01
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Abstract

This study were performed for the effects of Panax ginseng on the side effect of Cyclophosphamide to splenic tissue in the Rats. The experimental animals were divided into control group, test group by the way of the method treatment of the drug. Each group was sacrificed and stained in accordance with the schedule and observed under light microscope. The results of this study were as follows : 1. After the ginseng extract administration rat's weight and volume were similarly increased than normal and control group. 2. The decrease of the numbers of the splenic tissue after treatment of cyclophosphamide(CP) were recovered with prescription of the ginseng extract; the decrease of white pulp, red pulp, marginal zone were recovered. 3. Increased macrophage in red pulp of splenic tissue with administration of CP were disapeared after treatment of ginseng extract.

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