Journal of Korean Society of Occupational and Environmental Hygiene (한국산업보건학회지)

Korean Industrial Hygiene Association (한국산업보건학회)
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Blood Toluene and Urine Hippuric Acid Concentrations of Occupationally Toluene-exposed Workers

톨루엔 폭로 근로자의 혈중 톨루엔 및 요중 마뇨산 농도

  • Yang, Jung Sun (Industrial Health Research Institute Korea Industrial Corporation) ;
  • Kang, Seong Kyu (Industrial Health Research Institute Korea Industrial Corporation) ;
  • Kim, Ki Woong (Industrial Health Research Institute Korea Industrial Corporation) ;
  • Lee, Jong Sung (Industrial Health Research Institute Korea Industrial Corporation) ;
  • Cho, Young Sook (Industrial Health Research Institute Korea Industrial Corporation) ;
  • Chung, Ho Keun (Industrial Health Research Institute Korea Industrial Corporation)
  • 양정선 (한국산업안전공단 산업보건연구원) ;
  • 강성규 (한국산업안전공단 산업보건연구원) ;
  • 김기웅 (한국산업안전공단 산업보건연구원) ;
  • 이종성 (한국산업안전공단 산업보건연구원) ;
  • 조영숙 (한국산업안전공단 산업보건연구원) ;
  • 정호근 (한국산업안전공단 산업보건연구원)
  • Published : 1993.11.30
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Abstract

Toluene in air and blood and hippuric acid in urine were checked for the 41 female workers who are exposed to toluene and have normal liver function in shoe making factories in July, 1993. Toluene in air was sampled with charcoal by personal air sampler at least 4 times and analyzed by gas chromatography. At the end of shift, blood and spot urine were collected with a vacuum tube containing EDTA and a polyethylene bottle for detecting blood toluene and urine hippuric acid and analyzed by gas chromatography and high performance liquid chromatography. Means of air and blood toluene and urine hippuric acid concentrations were 34.35ppm, 0.360mg/L, and 1.78g/g creatinine, respectively. Toluene in air showed a good correlation with hippuric acid in urine(r=0.4503) and toluene in blood(r=0.4596). The hippuric acid in urine and toluene in blood corresponded 10 exposure of 100ppm toluene in air were 2.628g/g creatinine and 0.481mg/L. Blood toluene and urine hippuric acid expected ratio were not correlated to the obesity index and working duration, however increased with age.

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