참고문헌
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Ann. Rev. Nutr.
v.5
Vitamin
$B_{12}$ -folate interrelationship Shane,B.;Stokstad,E.L.R. - Vitamins and Hormones v.45 Folypolyglutamate synthesis and role in the regulation of one-carbon metabolism Shane,B.
- Science v.257 Agencies split on nutrition advice Palca,J.
- FASEB J. v.4 Dihydrofolate reductase as a therapeutic target Schweitzer,B.I.;Dicker,A.P.;Bertino,J.R.
- Am. J. Clin. Nutr. v.50 Folic acid safety and toxicity : A brief review Butterworth,C.E.;Tamura,T.
- Cancer Res. v.49 Inherent resistance of human squamous carcinoma cell lines to methotrexate as a result of decreased polyglutamylation of this drug Pizzorno,G.;Chang,Y.M.;McGuire,J.J.;Bertino,J.R.
- Cancer Res. v.48 Role of methotrexate polyglutamates in methotrexate and sequential methotrexate-5-fluorouracil-mediated cell kill McGuire,J.J.;Mini,E.;Hsieh,P.;Bertino,J.R.
- Proceedings of the sixth international conference on pteridines and related biogenic amines and folates Advances in antifolate development Kisliuk,P.L.;Blau,N.(ed.);Curtius,H.C.(ed.);Levine,R.(ed.);Yin,J.(ed.)
- Cancer Res. v.50 Activity of the thymidylate synthase inhibitor 2-dsamino-N10-propargyl-5, 8-dideazafolic acid and related compounds in murine(L1210) and human(W1L2) systems in vitro and in L1210 in vivo Jackman,L.A.;Taylor,G.A.;O'Conner,B.M.;Bishop,J.A.;Moran,R.G.;Calvert,A.H.
- Biochem. Pharmacol. v.41 Studies on the mechanism of antitumor action of 2-des-amino-2-methyi-5,8-dideazaisofolic acid Hagan,R.L.;Duch,D.S.;Smith,G.K.;Hanlon,M.H.;Shane,B.;Freisheim,J.H.;Hynes,J.B.
- Cancer Res. v.51 ICID 1964, a quinazoline antifolate thymidylate synthase inhibitor that is a potent inhibitor of L1210 tumor cell growth in vitro and in vivo : A new agent for clinical study Jackman,A.L.;Taylor,G.A.;Gibson,W.;Kimbell,R.;Brown,M.;Calvert,A.H.;Judson,I.R.;Hughes,L.R.
- J. Med. Chem. v.33 Synthesis and biological activity of an acyclic analogue of 5,6,7,8-tetrahydrofolic acid, N-[4-[[3-(2,4-diamino-1,6-dihydro-6-oxo-5-pyrimidinyl)propyl]amino]-benzoyi]-L-glutamic acid Kelly,J.L.;McLean,E.W.;Cohn,N.K.;Edeistein,M.K.;Duke,D.S.;Smith,G.K.;Hanlon,M.H.;Ferone,R.
- Cancer Res. v.49 Inhibition of glycinamide ribonucleotide formyltransferase and other folate enzymes by homofolate polyglutamates in human lymphoma and murine leukimia cell extracts Thorndike,J.;Gaumont,Y.;Kisliuk,R.L.;Sirotnak,F.M.;Murthy,B.R.;Nair,M.G.;Piper,J.R.
- J. Biol. Chem. v.264 A new folate antimetabolites, 5, 10-dideaza-5, 6, 7, 8-tetrahydrofolate is a potent inhibitor of de novo purine synthesis Beardsley,G.P.;Moroson,B.A.;Taylor,E.C.;Moran,R.G.
- Cancer Res v.50 In vivo and in vitro metabolism of 5-deazaacy-clotetrahydrofolate, an acyclic tetrahydrofolate analogue Hanlon,M.H.;Ferone,R.;Mullin,R.J.;Keith,B.R.
- Cancer Res. v.49 Induction of Hl-60 leukemia cell differentiation by the novel antifolate 5, 10-dideazatetrahydrofolic acid Sokoloski,J.A.;Beardsley,G.P.;Sartorelli,A.C.
- Method in Enzymology v.151 Amplification of genes in somatic mammalian cells Schimke,R.T.;Roos,D.S.;Brown,P.C.
- Cancer Res. v.48 Role of folypolyglutamate synthetase in the regulation of methotrexate polyglutamate formation in H35 hepatoma cells Johnson,T.B.;Nair,M.G.;Galivan,J.
- Cancer Res. v.48 Impaired polyglutamylation of methotrexate as a cause of resistance in CCRF-CEM cells after short-term, high-dose treatment with this drug Pizzorno,G.;Mini,E.;Coronello,M.;McGuire,J.J.;Moroson,B.A.;Cashmore,A.R.;Dreyer,R.N.;Lin,J.;Mazzei,T.;Periti,P.;Bertino,J.R.
- J. Biol. Chem. v.268 Regulation of folate and one carbon metabolism in mammalian cells Kim,J.;Lowe,K.E.;Shane,B.
- Ph. D. dissertation , Dept. of Nutritional Sciences, University of California at Berkeley Cytotoxicity and metabolism of antifolates Kim,J.
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J. Biol. Chem.
v.265
Indentification and characterization of a mutation in the dihydrofolate reductase gene from the methotrexate-resistant Chinese hamster ovary cell line
$pro^{-3}\;Mtx^{RMt}$ Dicker,A.P.;Volkenandt,M.;Schweitzer,B.L.;Banerjee,D.;Bertino,J.R. - J. Biol. Chem. v.263 Gene amplification in cultured cells Schimke,R.T.
- Cell v.57 Recent progress in understanding of mammalian DNA amplification Stark,G.R.;Debatisse,E.G.;Wahl,G.M.
- J. Biol. Chem. Role of folylpolyglutamate synthease in the metabolism and cytotoxicity of 5-deazaacyclotetrahydrofolate, an anti-purine drug Kim,J.;Shane,B.
- Proc. Natl. Acad. Sci. USA v.78 Methotrexate-resistant Chinese hamster ovary cells have amplified a 135-kilobase-pair region that includes the dihydrofolate reductase gene Milbrandt,J.D.;Heintz,N.H.;White,W.C.;Rothman,S.M.;Hamlin,J.L.
- Cancer Res. v.45 Cytotoxic effects of folate antagonists against methotrexate-resistant human leukemia lymphoblast CCRF-CEM cell lines Mini,E.;Moroson,B.A.;Franco,C.T.;Bertino,J.R.
- J. Med. Chem. v.32 Inhibition of mammalian folylpolyglutamate synthetase and human dihydrofolate reductase by 5,8-dideaza analogues of folic acid and aminopterin bearing a terminal L-ornithine Patil,S.A.;Shane,B.;Freisheim,J.H.;Singh,S.K.;Hynes,J.B.
- Proc. Natl. Acad. Sci. USA v.89 Expression cloning of human cDNA encoding folypoly(γ-glutamate) synthetase and determination of its primary structure Garrow,T.A.;Admon,A.;Shane,B.
- Mol. Cell. Biol. v.9 Nonsence mutation in the dihydrofolate reductase gene affect RNA processing Urlaub,G.;Mitchell,P.J.;Ciudad,C.J.;Chasin,L.A.
- Bio Essays v.13 Multidrug resistant transgenic mice as a novel pharmacologic tool Mickish,G.H.;Pastan,I.;Gottesman,M.M.
- Cancer Res. v.50 Reversal of the multidrug resistance phenotype with cremophor EL, a common vehicle for water-insoluble vitamins and drugs Woodcock,D.M.;Jefferson,S.;Linsenmeyer,M.E.;Crowther,P.J.;Chojnowski,G.M.;Williams,B.;Bertoncello,I.
- Cancer Res. v.48 Genes amplified and overexpressed in human multidrug-resistant cell lines Bliek,A.M.V.;Baas,F.;Velde-Koerts,T.V.;Biedler,J.L.;Meyers,M.B.;Ozols,R.F.;Hamilton,T.C.;Joenje,H.;Borst,P.
- Cancer Res. v.50 Comparison of the cytotoxic effects of the high-and low-molecular-weight anticancer agents on multidrug-resistant Chinese hamster ovary cells in vitro Miyamoto,Y.;Oda,T.;Maeda,H.
- Mol. Cell. Biol. v.10 Two members of the mouse mdr gene family confer multidrug resistance with overlapping but distinct drug specificities Devault,A.;Gros,P.
- Mol. Cell. Biol. v.10 Physical mapping amplification and overexpression of the mouse mdr gene family in multidrug-resistant cells Raymond,M.;Rose,E.;Housman,D.E.;Gros,P.
- Cell v.71 Separation of drug transport and chloride channel functions of the human multidrug resistance P-glycoprotein Gill,D.R.;Hyde,S.C.;Higgins,C.F.;Valverde,M.A.;Mintenig,G.M.;Sepulveda,F.V.