Microbiology and Biotechnology Letters (한국미생물·생명공학회지)

The Korean Society for Microbiology and Biotechnology (한국미생물·생명공학회)
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Screening of Microorganisms having Antiviral Activity against HIV Virus from Soil

토양으로부터 HIV 바이러스에 항바이러스 활성을 나타내는 미생물의 탐색

  • 김성욱 (한국과학기술연구원 유전공학연구소 생물소재연구 그룹) ;
  • 이상한 (한국과학기술연구원 유전공학연구소 생물소재연구 그룹) ;
  • 정태숙 (한국과학기술연구원 유전공학연구소 생물소재연구 그룹) ;
  • 문석식 (공주대학교 화학과) ;
  • 이종교 (한국화학연구소 의약활성연구실) ;
  • 이항우 (한국과학기술연구원 유전공학연구소 생물소재연구 그룹) ;
  • 이원영 (연세대학교 의과대학 미생물학교실) ;
  • 복성해 (한국과학기술연구원 유전공학연구소 생물소재연구 그룹)
  • Published : 1993.10.01
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Abstract

For screening of the antiviral agent from soil, about 520 strains of microorganisms were evaluated for their antiviral activity, About 6.9% of strains showed more than 95% antiviral activity against Herpes Simples Virus (HSV)-1. Two strains among 30 strains active against HSV-1 virus showed a quite strong activity against human immunodeficiency virus.

Keywords

References

  1. Scientific American v.256 Antiviral therapy Hirsch,M.S.;J.C.Kaplan
  2. Virology Chou,S.;T.C.Merigan
  3. Antiviral Res. v.4 Screening for new compounds with antiherpes activity Alarcon,B.;J.C.Lacal;J.M. Fermandez-sousa;L.Carrasco
  4. Antiviral Res. v.3 A colorimetric assay for the measurement of the sensitivity of herpes simplex viruses to antiviral agents Mclaren,C.;M.N.Ellis;G.A.Hunter
  5. Antiviral Res. v.5 The need for new antiviral agents Freestone,D.S.
  6. Nature v.202 Selection of media for isolation of Streptomyces Kuster,E.;S.T.Williams
  7. J. Ferment Technol. v.65 Humic acid-Vitamin agar a new medium for the selective isolation of soil actinomycetes Hayakawa,M.;H.Nonomura
  8. J. Ferment. Technol. v.65 Efficacy of artificial humic acid as a selective nutrient in HV agar used for the isolation actinomycetes Hayakawa,M.;H.Nonomura
  9. 신규 의약품 스크리닝 기술개발에 관한 연구(Ⅲ) 지옥표(외)
  10. J. Antibiot. v.36 Retrostatin a new specific enzyme inhibitor against avian myeloblastosis virus reverse transcriptase Nishio,M.;A.Kuroda;M.Suzuki;K.Ishimaru;S.Nakamura;R.Nomi
  11. J. Antibiot. v.38 Inhibition of reverse transcriptase by limocrocin Hauajima,S.K.;Ishimaru;K.Sakano;S.Kumar Roy;Y.Inouye;S.Nakamura
  12. J. virological methods v.20 Repid and automated tetrazolium-based colorimetric assay for the detection of anti-HIV compounds Pauwels,R.;E.De clercq;J.Desmyter;J.Balzarins;P.Goubau;P.Herdewijin;H.Vanderhaeghe;M.Vandeputte
  13. J. Antibiot. v.38 Biological properties of Sterptonigrin derivatives Inouye,Y.;H.Okada;S.K.Roy;T.Miyasaka;S.Hibino;N.Tanaka;S.Nakamura
  14. J. Antibiot. v.39 Effects of Streptonigrin derivatives and Sakyomicin A on the respiration of isolated rat liver mitochondria Inouye,Y.H.;Okada,J.;Uno, T. Arai;S.Nakamura
  15. Japan J. Cancer Res. v.77 Inhibition by Sakyomicin A of avian myeloblastosis virus reverse transcriptase and Proliferation of AIDS-associated virus (HTLV-III/LAV) Tanaka,N.;T.Okabe;N.Tanaka;Y.Take;Y.Inouye;S.Nakamura;H.Nakashima;N.Yamamoto