Archives of Pharmacal Research
- 제16권1호
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- Pages.68-70
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- 1993
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- 0253-6269(pISSN)
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- 1976-3786(eISSN)
Synthesis of 2,5Bis(2'-piperidymethyl)piperidine and Related Compounds
- Hammouda, Metwally (Chemistry Department, Faculty of Science, Mansoura University) ;
- Kandeel, Ex-el-Din (Chemistry Department, Faculty of Science, Mansoura University) ;
- Hamama, Wafaa (Chemistry Department, Faculty of Science, Mansoura University) ;
- Afsah, Elsayed (Chemistry Department, Faculty of Science, Mansoura University)
- 발행 : 1993.03.01
초록
The triketones 3-6 were obtained by alkylation of cyclopentanone or cyclohexanone with the appropriate cycloalkanone bis-mannich base (1) or (2). Schmidt reaction of the tricketones 3-6 afforded the corresponding trcyclic lactames 7-10 respectively. reduction of 7 and 9 gave compounds 11 and 12 respectively.
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