Journal of Ginseng Research
- Volume 17 Issue 2
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- Pages.135-138
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- 1993
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- 1226-8453(pISSN)
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- 2093-4947(eISSN)
Aqueous Fraction from Korean Red Ginseng Inhibits the Protein Phosphorylation Induced by Tumor Promoter
고려홍삼의 수용성 분획은 종양촉진인자에 의해 유도되는 단백질 인산화반응을 억제한다
- Park, Hwa-Jin (Department of Biochemical Pharmacology Korea Ginseng & Tobacco Research Institute) ;
- Park, Kyeong-Mee (Department of Biochemical Pharmacology Korea Ginseng & Tobacco Research Institute) ;
- Rhee, Man-Hee (Department of Biochemical Pharmacology Korea Ginseng & Tobacco Research Institute) ;
- Park, Ki-Hyun (Department of Biochemical Pharmacology Korea Ginseng & Tobacco Research Institute)
- Published : 1993.08.01
Abstract
Aqueous fractions from Korean red ginseng inhibited the phosphorylations of 40 KD and 20 KD polypeptides which were induced by phorbol-12-myristate-13-acetate (100 nM) in human platelets. Much more carbohydrates were contained in the aqueous fractions than proteins. An aqueous fraction extracted with methanol, mainly, consists of glycoproteins, molecular weights of which were below 18 KD. We may infer that the aqueous fraction from Korean red ginseng do antitumorous and antiplatelet functions.
Keywords
- Aqeous fraction from Korean red ginseng;
- antitumorous activity;
- inhibition on phosphorylation of 40 KD and 20 KD