생약학회지 (Korean Journal of Pharmacognosy)
- 제24권4호
- /
- Pages.313-318
- /
- 1993
- /
- 0253-3073(pISSN)
- /
- 2288-9299(eISSN)
포공영의 항위염 작용
The Antigastritic Effect of Taraxaci Herba
- Lee, Eun-Bang (Natural Products Research Institute, Seoul National University) ;
- Kim, Jung-Keun (Natural Products Research Institute, Seoul National University) ;
- Kim, Ok-Kyung (College of Natural Science, Seoul Woman's University)
- 발행 : 1993.12.30
초록
The methanol extract of Taraxaci Herba was found to have inhibitory effect on the gastric lesion induced by HCl-ethanol. The systematic fractionation of the methanol extract resulted in positive action with water fraction in the gastric lesion. It also showed significant inhibition of gastric lesion induced by HCl-aspirin and absolute ethanol, but did not prevent indomethacin induced gastric lesion. This fraction did not affect basal gastric acid secretion but showed a decrease of pepsin activity in pylorus-ligated rats.