Pharmacologic Activities of Saikosaponins (II) -Effects of Saikosaponin on Metabolizing Enzymes and Lipid Peroxide Contents in Liver-

시호(柴胡) 사포닌류(saikosaponins)의 약리작용(II) -Saikosaponin이 간 대사효소계 및 과산화지질 함량에 미치는 영향-

As a part of pharmacological studies of saikosaponins, which were reported to exhibit diverse biological activities especially concerning with liver function, effects of saikosaponin on metabolizing enzymes and lipid peroxide contents in liver were examined. As the result, UDP-glucose dehydrogenase activity and lipid peroxidation which were due to acetaminophen were inhibited by saikosaponin treatment. But other metabolizing enzyme activities were not modified.