The Effects of Meliae toosendan Fructus on Liver Function (I) -Effects of Each Fractions from Meliae toosendan Fructus on Drug Metabolism Enzyme System and Bile Secretion-

천련자 추출물이 간기능(肝機能)에 미치는 영향(影響)(I) -천련자의 분획이 약물대사효소계 및 담즙분비에 미치는 영향-

Meliae toosendan Fructus is the fruit of Melia toosendan $S_{IEB}$. et $Z_{UCC}$. (Meliaceae), which is written in oriental terminology as clearing heat and drying dampness, and also explained using liver, stomach and small intestine for channels entered. Among the five fractions prepared from methanol whole extractive of the herb, the chloroform fraction which suggests the presence of triterpenoid, flavonoid and alkaloid stimulated the activities of drug metabolizing enzymes and bile secretion and lowered the serum transaminase activities of liver damaged by carbon tetrachloride.