The Korean Journal of Physiology
- Volume 27 Issue 2
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- Pages.217-225
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- 1993
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- 0300-4015(pISSN)
Effects of Centrally Administered Angiotensin ll Receptor Antagonists on the Cardiovascular and Hormonal Responses to Hemorrhage in Conscious SHR
- Seo, Il-Sook (Department of Physiology, School of Medicine, Kyungpook National University) ;
- Yang, Eun-Kyoung (Department of Physiology, School of Medicine, Kyungpook National University) ;
- Park, Jae-Sik (Department of Physiology, School of Medicine, Kyungpook National University) ;
- Kim, Hyeong-Jin (Department of Physiology, School of Medicine, Kyungpook National University) ;
- Lee, Won-Jung (Department of Physiology, School of Medicine, Kyungpook National University)
- Published : 1993.12.01
Abstract
The role of endogenous brain angiotensin ll (Ang ll) in mediating the cardiovascular and vasopressin responses to hemorrhage was assessed in conscious spontaneously hypertensive rats (SHR), and normotensive Wistar-Kyoto (WKY) rats. Artificial cerebrospinal fluid (aCSF) with or without losartan (DuP 753), a specific Ang ll receptor subtype I